FindTrial
Sign In

Study of genetic risk factors and clinical presentation of Indian patients with unexplained heart enlargement.

Evaluation of Genotype-Phenotype correlation in Idiopathic Dilated Cardiomyopathy (iDCM) in an Indian cohort.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/12/022329
Enrollment
200
Registered
2019-12-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I420- Dilated cardiomyopathy

Interventions

None listed

Sponsors

Department of Science and Technology Science and Engineering Research Board
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Previously diagnosed patients with dilated cardiomyopathy. Patients with a presentation of an ejection fraction chambers and hypokinetic LV

Exclusion criteria

Exclusion criteria: Dilated cardiomyopathy due to valvular disease or hypertensive heart disease.

Design outcomes

Primary

MeasureTime frame
Genetic testing will reveal the nature of mutations responsible for cardiomyopathy. Immediate family members will be informed to undergo tests in case the mutation is inherited. Early detection of mutations will lead to better prognosis in the patients. If the family members test negative for the mutation further medical intervention is not necessary.Timepoint: 3 years—

Secondary

MeasureTime frame
Cascade genetic screening in consenting first degree relativesTimepoint: 3 years—

Countries

India

Contacts

Public ContactDr Moka Rajasekhar

Manipal School of Life Sciences

rsmoka@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026