Skip to content

Incidence of hypotension after spinal anaesthesia in normotensive and preeclamptic women undergoing caesarean section

Comparison of haemodynamic response and phenylephrine requirement following spinal anaesthesia in normotensive and preeclamptic women undergoing caesarean section: a prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/12/022321
Enrollment
100
Registered
2019-12-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O149- Unspecified pre-eclampsia

Interventions

Control Intervention1: Healthy parturients: hyperbaric 0.5% bupivacaine 10 mg (2ml)intrathecally Control Intervention2: Preeclamptic parturients: hyperbaric 0.5% bupivacaine 10 mg (2ml) intrathecally

Sponsors

Dr S N Medical College Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women of age group 18-35 years belonging to ASA grade 2 Body Mass Index (BMI) between 20-35 kg/m2 undergoing cesarean section under spinal anesthesia including healthy parturients Preeclamptic parturients (systolic blood pressure of 140 mmHg or higher, or a diastolic blood pressure of 90 mmHg or higher, or both, associated with proteinuria > 3 g/24 hours).

Exclusion criteria

Exclusion criteria: Patients refusal Known hypersensitivity to local anaesthetics Infection at the site of injection History of bleeding disorders or patients on anticoagulants Preterm pregnancies less than 34 weeks gestation, twin pregnancy; those with signs of imminent eclampsia Patients with cardiac disease (like heart blocks, dysarrythmias), chronic hypertensives, diabetics, renal or other organ system disease which preclude choice of spinal anaesthesia Anatomical abnormality of spine.

Design outcomes

Primary

MeasureTime frame
To compare the haemodynamic responseTimepoint: End of surgery

Secondary

MeasureTime frame
1.The total doses of Phenylephrine 2.Neonatal outcome in terms of umbilical cord pH, APGAR score 3.Intraoperative side effects / complications Timepoint: End of surgery

Countries

India

Contacts

Public ContactYuvraj S

Dr. S.N. medical collage, Jodhpur

geetamanojkamal@gmail.com09414803554

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026