Health Condition 1: D331- Benign neoplasm of brain, infratentorial
Conditions
Interventions
Intervention1: Dexmedetomidine: Dexmedetomidine 0.25 microgm/kg/hr , continuous infusion through infusion pump, from the time of start of anaesthesia till dura closure
Control Intervention1: Placebo N
Sponsors
Dr Deepa Suvarna
Eligibility
Inclusion criteria
Inclusion criteria: 1 ASA I to ASA III 2 Both genders 3 Patients undergoing elective sitting position intracranial tumour surgery with GCS more than 9.
Exclusion criteria
Exclusion criteria: 1 Refusal of patient to participate in the study. 2 ASA IV 3 Pregnant patients 4 Patients with baseline heart rate less than 55/minute 5 Patients with heart blocks 6 Allergic to drugs . 7 History of drug abuse. 8 Preoperative aphasia. 9 Preoperatively foreseen delayed extubation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure and heart rateTimepoint: Will be recorded at 5 time points.Before anaesthesia induction-(baseline),at placement of head frame,at dural incision, at the end of tumour resection ,at the end of dural closure. Intraoperatively episodes of hypotension or hypertension will be monitored .Haemodynamic monitoring will be continued till the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Total Opioid requirementTimepoint: At the end of surgery;Recovery endpointsTimepoint: At the end of surgery | — |
Countries
India
Contacts
Public ContactDr Srilaxmi Ananthprasad Rao
Topiwala National Medical college and B.Y.L.Nair Hospital,Mumbai
Outcome results
None listed