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A study on risk factors for severe flu

A clinical study on risk factors for severe Influenza A&B

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/12/022222
Enrollment
400
Registered
2019-12-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J09X- Influenza due to identified novelinfluenza A virus

Interventions

None listed

Sponsors

Kasturba Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Influenza A&B patients diagnosed during my study period in Kasturba Medical college are considered as a cohort among which following are considered to have severe disease and rest not having severe disease . Influenza patients with any one of the following is considered as severe influenza 1)Pneumonia-clinical and radiologically proven 2)Acute respiratory distress syndrome-Berlin criteria 2012 3)Acute kidney injury-KDIGO classification 2012 4)Hepatitis-Serum bilirubin more than 2mg/dl and AST/ALT ratio more than 2 5)Myocarditis-Electrocardiography,2D-ECHO,cardiac biomarkers. 6)Thrombocytopenia-platelet count less than one lakh per microliter 7)Encephalitis-altered sensorium, seizures 8)Septic shock-Survival sepsis guidelines

Exclusion criteria

Exclusion criteria: Who are unwilling to participate are not included, who are not admitted in Kasturba hospital.

Design outcomes

Primary

MeasureTime frame
Primary outcome To identify risk factors contributing for severe influenza A&B Secondary outcome- a)To observe common secondary bacterial infections among severe influenza A&B patients b)To observe antimicrobial utilization pattern in severe influenza A&B patients c)To assess mortality rate in severe influenza A&B patientsTimepoint: september2019 to august2021

Secondary

MeasureTime frame
Secondary outcome- a)To observe common secondary bacterial infections among severe influenza A&B patients b)To observe antimicrobial utilization pattern in severe influenza A&B patients c)To assess mortality rate in severe influenza A&B patientsTimepoint: september2019 to august2021

Countries

India

Contacts

Public ContactDrAddepalli Surya Vamsi

Kasturba Medical College

drmuralidharvarma@yahoo.co.in08985479389

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026