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CT with and without Contrast Injection: Effect on Kidney Function in Patients with Acute Pancreatitis

COMPARISON OF RENAL PARAMETERS IN PATIENTS WITH ACUTE NECROTIZING PANCREATITIS UNDERGOING NON-CONTRAST CT VERSUS CONTRAST ENHANCED FOR FOLLOW UP IMAGING: A RANDOMISED CONTROL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/12/022206
Enrollment
120
Registered
2019-12-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K859- Acute pancreatitis, unspecified

Interventions

Intervention1: Non-contrast computed tomography: Computed tomography. No intravenous contrast agent will be administered. Control Intervention1: Contrast enhanced computed tomography: computed tomogra

Sponsors

Manavjit Sandhu
Lead Sponsor
Pankaj Gupta
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients with acute pancreatitis between age of 12 years and 70 years

Exclusion criteria

Exclusion criteria: Patients allergic to intravenous contrast agent Patients with serum creatinine more than 2mg/dL Pregnant females Refusal to give consent Known case of chronic pancreatitis or acute on chronic pancreatitis Proven or suspected pancreatic cancer drainage of the pancreatic collection already done at the time of presentation to the hospital

Design outcomes

Primary

MeasureTime frame
Acute Kidney InjuryTimepoint: Days 1, 2, 3 (in reference to the CT scan) and the time of discharge from the hospital

Secondary

MeasureTime frame
Length of hospitalisationTimepoint: During 1st admission;MortalityTimepoint: In hospital or 1 month after discharge;Need for dialysisTimepoint: During hospitalisation;Need for drainage of pancreatic collectionTimepoint: During hospitalisation;Need for intensive care unit (ICU) admission and length of ICU stayTimepoint: During 1st admission;Need for surgeryTimepoint: During hospitalisation;Radiation dose from all computed tomography scans performed for management of acute pancreatitisTimepoint: During hospitalisation

Countries

India

Contacts

Public ContactDr Pankaj Gupta

Postgraduate Institute of Medical Education and Research

pankajgupta959@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 10, 2026