Study comparing the pain relief by two medicines known as local anaesthetics on the donor site of split thickness skin graft surgery.

A study comparing the effectiveness of 0.5% Bupivacaine vs 0.5%Ropivacaine soaked surgical dressing for pain relief at STSG donor site- A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/12/022204

Enrollment

Registered

2019-12-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L768- Other intraoperative and postprocedural complications of skin and subcutaneous tissue

Interventions

Intervention1: Using dressing soaked in 0.5% ropivacaine at the donor site.: Post operatively, the donor site will be dressed using calcium alginate dressing which is instilled with 0.5% ropivacaine a

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient older than 18 years and lesser than 65 years 2.Patient needing a thin skin graft 3.Patient who read the information letter and signed the informed consent

Exclusion criteria

Exclusion criteria: 1. Contraindication to one of the medicine used (allergy, intolerance, potential drug interaction) 2. Sensory disturbances of the lower limbs 3. Cognitive disturbances not allowing investigations • Pregnant or lactating women • Polytrauma

Design outcomes

Primary

Measure	Time frame
To assess post-operative pain relief at the STSG donor site. Timepoint: The pain at the donor site will be assessed in the first hour post-op, followed by every 6 hours in the ward for the next 48hours. The pain score will be assessed using the NRS scale.	—

Secondary

Measure	Time frame
To assess the need for post operative usage of opioids and other pain killers. To assess the side effects related to usage of narcotics. Timepoint: 48 HOURS	—

Countries

India

Contacts

Public ContactNirupama Arulappan

CHRISTIAN MEDICAL COLLEGE

sajanpg@cmcvellore.ac.in8098118456

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026