Health Condition 1: F05- Delirium due to known physiological condition
Conditions
Interventions
Intervention1: Melatonin: Melatonin is essential for delirium. It helps to reset the sleep cycle in delirium. Melatonin tablets will be given to the delirium patients. Dose range is 3-9 mg as per requ
Sponsors
King Georges Medical University
King Georges Medical University
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosis of Delirium qualifying according to ICD-10 (international classification of disease-10). 2. Age 60-95 years 3. Patientâ??s family members willing to give consent.
Exclusion criteria
Exclusion criteria: 1. Past history of seizure, ischemic or haemorrhagic CVA or traumatic brain injury and encephalitis. 2. IQCODE score >= 3.5 to exclude dementia. 3. Unreliable informants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| S100B is a calcium binding protein which increases in delirium. Melatonin is a important neurotransmitter which is essential for sleep induction. The hypothesis that melatonin decreases the S100B protein and might be useful for the treatment of delirium.Timepoint: SEVEN DAYS | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To study the severity of delirium before and after giving exogenous melatonin. 2.To study the relation between S100B protein level and the severity of delirium. Timepoint: SEVEN DAYS | — |
Countries
India
Contacts
Public ContactMithun Biswas
King Georges Medical University
Outcome results
None listed