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Study on use of vaccines like MMR and PPD in wart

A COMPARATIVE STUDY ON THE EFFICACY OF INTRALESIONAL MMR VACCINE AND INTRALESIONAL PURIFIED PROTEIN DERIVATIVE IN VERRUCA VULGARIS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/11/022192
Enrollment
30
Registered
2019-11-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue

Interventions

Intervention1: MEASLES,MUMPS, RUBELLA VACCINE: 0.3ML GIVEN INTRALESIONAL ,EVERY 2 WEEKS UPTO 3 DOSES OR RESOLUTION (WHICHEVER IS EARLIER) Intervention2: PURIFIED PROTEIN DERIVATIVE: 0.3ML INRALESIONAL

Sponsors

SHUNMADHI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. 30 patients aged 12-25 years with verruca vulgaris(less than 20 in number) attending the Dermatology OPD during the study period. 2. Patient who has not undergone any prior systemic or topical treatment. 3. Those who are giving consent to participate in the study. 4. Those who are willing for follow up.

Exclusion criteria

Exclusion criteria: 1. Prior known allergic response to MMR vaccine 2. Patients who received any other treatments for their warts before enrolment. 3. Patients with H/O asthma,allergic skin disorders, meningitis or convulsions 4. Patient with acute febrile illness or signs of any inflammation or infection. 5. Patients with Hepatitis B & Hepatitis C infection 6. Patients with immunosuppression/ HIV Infection 7. Patients with anogenital warts 8. Patients with H/O TB 9. Induration measuring

Design outcomes

Primary

MeasureTime frame
1.intralesional MMR is better than intralesional PPD 2.Intralesional vaccine is effective against distant wart Timepoint: EVERY 2 WEEKS FOR 3 MONTHS THEN EVERY MONTH UPTO 6 MONTHS OF INITIAL DOSE

Secondary

MeasureTime frame
1. To identify the efficacy of Treatment for local and distant warts. 2. To identify the better treatmentregimen for Verruca vulgaris. 3. To identify the side effects and recurrence rate following treatment. Timepoint: 1 YEAR

Countries

India

Contacts

Public ContactSHUNMADHI S

MADRAS MEDICAL COLLEGE

deepaderm@gmail.com9443057422

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026