A clinical trial to study the effect of phacoemulsification and manu small incision cataract surgery on endothelial cell changes

Endothelial cell loss analysis in phacoemulsification versus small incision cataract surgery: A randomised study

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/11/022169

Enrollment

266

Registered

2019-11-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H251- Age-related nuclear cataract

Interventions

Intervention1: Phacoemulsification: Surgical intervention after randomising the groups Control Intervention1: Manual Small Incision Cataract Surgery: Surgical intervention after randomising the groups

Eligibility

Inclusion criteria

Inclusion criteria: Senile cataract of Nuclear grade III-IV (LOCS II classification)

Exclusion criteria

Exclusion criteria: 1. Endothelial cell density less than 1500 cells/mm3 2. History of previous ocular surgery 3. History of any other coexisting oular disease 4. History of any intraoperative surgical complication

Design outcomes

Primary

Measure	Time frame
To evaluate and compare endothelial cell changes in eyes undergoing phacoemulsification or manual small incision cataract surgery Timepoint: After 6 weeks from cataract surgery	—

Secondary

Measure	Time frame
1 . To compare the best corrected visual acuity (BCVA) in both the groups 2. To correlate the average phacoemulsification time (APT) used in phacoemulsification group with endothelial cell loss 3. To compare the results in different axial length groups Timepoint: After 6 weeks from cataract surgery	—

Countries

India

Contacts

Public ContactSanjiv Kumar Gupta

King Georges Medical University

sanjiv204@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026