Health Condition 1: 4- Measurement and Monitoring
Conditions
Interventions
Intervention1: Laryngoscopy and intubation, magnesium sulphate, dexmedetomidine
: In the study two decided drugs will be compared
Magnesium sulphate will be used as 50mg/kg or Dexmedetomidine in 0.25
Sponsors
UCMS and GTB hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patient undergoing elective surgery under general anaesthesia and requiring laryngoscopy and endotracheal intubation Patient belonging to ASA grade I and II Patient with Mallampati grade I and II Patient of either gender Patient of age group 18-60 yrs
Exclusion criteria
Exclusion criteria: Patient not willing to participate in the study Patient with the history of difficult intubation Patient with anticipated difficult airway Patient having BMI >30kg/m2 Patient having history of cardiovascular, cerebral, renal, hepatic, bronchial, endocrine disease or psychiatric disorder Patient on anti-hypertensive, hypnotic or narcotic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in SBP following laryngoscopy and intubation in the two groupsTimepoint: Preoperative (base line values) i.e. before infusion of study drug During medication at 5min, 10min Pre-induction of anaesthesia Just before laryngoscopy and intubation Post intubation at 1 min, 3min, 5min, 7min and 10min Then every 5 min till the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the heart rate between two groups following laryngoscopy and intubation To compare Diastolic and Mean blood pressure between two groups To compare post-operative pain by Numerical Rating score in two groups To compare post-operative sedation score in two groups Timepoint: Preoperative (base line values) i.e. before infusion of study drug During medication at 5min, 10min Pre-induction of anaesthesia Just before laryngoscopy and intubation Post intubation at 1 min, 3min, 5min, 7min and 10min Then every 5 min till the end of surgery | — |
Countries
India
Contacts
Public ContactKusum
UCMS and GTB hospital
Outcome results
None listed