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Advanced Radiotherapy in Carcinoma Breast.

Adjuvant Radiotherapy in breast cancer using Volumetric Modulated Arc Therapy (VMAT) technique: dosimetric comparison with 3D-Conformal Radiotherapy, and report on clinical outcomes.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/11/022151
Enrollment
29
Registered
2019-11-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast

Interventions

Intervention1: Nil.: Nil. Intervention2: Nil: Nil

Sponsors

Kasturba Medical College Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with breast cancer requiring adjuvant radiotherapy following either BCS or MRM, but cannot be adequately treated with 3D-CRT, and thereby require IMRT based RT planning. Criteria: a.Tumor coverage V95 b.Homogeneity Index > 0.1. c.V105 > 5% of the tumor. d.V10 e.Ipsilateral lung dose f.Internal mammary lymph node positive cases. g.B/L breast cancer. Willing to participate in the study and provides a voluntary informed consent.

Exclusion criteria

Exclusion criteria: 1. Metastatic disease, and patients being considered for loco-regional radiotherapy with an intent to palliation. 2. History of prior radiation, connective tissue disorders or other comorbidities that could put the patient at higher risk of developing treatment related toxicities.

Design outcomes

Primary

MeasureTime frame
Dosimetric comparison of tumor coverage and normal tissue exposure between VMAT technique with conventional 3DCRT Technique in adjuvant radiotherapy for breast cancer.Timepoint: September 2021

Secondary

MeasureTime frame
1.To report the acute toxicities of treatment. 2.To evaluate local control rates following VMAT based EBRT. 3.Record patient-perceived cosmetic outcomes of treatment. 4.Quality of Life Study.Timepoint: Till September 2021

Countries

India

Contacts

Public ContactDr Nikunj Patil

Kasturba Medical College, Manipal

tk.sharan@gmail.com9448625116

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026