Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with breast cancer requiring adjuvant radiotherapy following either BCS or MRM, but cannot be adequately treated with 3D-CRT, and thereby require IMRT based RT planning. Criteria: a.Tumor coverage V95 b.Homogeneity Index > 0.1. c.V105 > 5% of the tumor. d.V10 e.Ipsilateral lung dose f.Internal mammary lymph node positive cases. g.B/L breast cancer. Willing to participate in the study and provides a voluntary informed consent.
Exclusion criteria
Exclusion criteria: 1. Metastatic disease, and patients being considered for loco-regional radiotherapy with an intent to palliation. 2. History of prior radiation, connective tissue disorders or other comorbidities that could put the patient at higher risk of developing treatment related toxicities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dosimetric comparison of tumor coverage and normal tissue exposure between VMAT technique with conventional 3DCRT Technique in adjuvant radiotherapy for breast cancer.Timepoint: September 2021 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To report the acute toxicities of treatment. 2.To evaluate local control rates following VMAT based EBRT. 3.Record patient-perceived cosmetic outcomes of treatment. 4.Quality of Life Study.Timepoint: Till September 2021 | — |
Countries
India
Contacts
Kasturba Medical College, Manipal