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comparison of two toothpastes on microorganisms in orthodontic patients

Comparison of the antimicrobial effect of Chlorhexidine digluconate toothpaste and Colgate Total toothpaste on the Streptococcus mutans levels in orthodontic patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/11/022140
Enrollment
44
Registered
2019-11-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Chlorhexidine Gluconate toothpaste: Chlorhexidine Gluconate solution containing 0.004% w/w will be applied pea size twice a day for a period of 1 month Control Intervention1: Colgate To

Sponsors

Dr Deeksha S Innanje
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (1) Healthy patients (both genders) in the group of 14 to 25 years. (2) Patients requiring fixed orthodontic treatment (MBT, 0.022â?? in slot; 3M Unitek,Monrovia,Calif). (3) Patients with good general health (no significant medical history or drug use in the last month). (4) Patients with permanent dentition. (5) Patients without any periodontal diseases.

Exclusion criteria

Exclusion criteria: (1) Patients on systemic consumption of antibiotics or anti-inflammatory medications taken during the period of the study. (2) Patients with systemic diseases such as hormonal imbalances and bone diseases. (3) Patients with periodontal diseases. (4) Patients with carious or infiltrated restorations. (5) Patients with fractured teeth or presence of erosion.

Design outcomes

Primary

MeasureTime frame
Streptococcus mutans countTimepoint: samples will be collected on the day of allocation of toothpaste group and next sample will be taken after a month

Secondary

MeasureTime frame
PlaqueTimepoint: samples will be collected on the day of allocation of toothpaste group and next sample will be taken after a month

Countries

India

Contacts

Public ContactDr Shrinivas M Basavaraddi

SDM college of Dental Sciences and Hospital

deekshainnanje@gmail.com8762722888

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026