A new method to reduce the blackish discoloration of the tooth caused during the treatment of early childhood caries.

Efficacy of Glutathione biomolecule in reducing the tooth discoloration associated with silver diamine fluoride- A Split-mouth randomized controlled trial.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/11/022103

Enrollment

Registered

2019-11-21

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Silver Diamine Fluoride mixed with Glutathione aplication: SDF will be mixed with 20% GSH by weight under vigorous stirring until the solution is clear without any precipitates. The mix

Eligibility

Inclusion criteria

Inclusion criteria: Only children who sign the assent form (if applicable) and whose parents give a written consent will be included in the study

Exclusion criteria

Exclusion criteria: Children who refuse dental treatment and those with non-restorable or pulpally involved teeth (Teeth with pulp exposure, presence of an abscess or a sinus, obvious discoloration, and premature hypermobility) will be excluded

Design outcomes

Primary

Measure	Time frame
Improved esthetics while using Silver diamine fluorideTimepoint: after 48 hours and 14 days	—

Secondary

Measure	Time frame
caries arrest and managementTimepoint: evaluated after 6 months and 1 year	—

Countries

India

Contacts

Public ContactDr Karuna Y M

Manipal College of Dental Sciences, Mangalore, Karnataka

karuna.ym@manipal.edu9964116229

Outcome results