Health Condition 1: C910- Acute lymphoblastic leukemia [ALL] Health Condition 2: C920- Acute myeloblastic leukemia
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Jawaharlal Institute of Postgraduate Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: i. AML on intensive induction chemotherapy. ii. Relapsed acute leukemia on salvage chemotherapy.
Exclusion criteria
Exclusion criteria: 1. Patient not willing to give consent 2. Acute promyelocytic leukemia 3. Patient with documented infection (clinically/microbiologicaly) at the start of Induction/ salvage chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effect of sepsis bundle based protocol on 30 day mortality among patients with very high risk febrile neutropeniaTimepoint: The data will be collected for the first 30 days of intensive induction treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the clinical outcomes (change in MSOFA score at 48 hours ,occurence of septic shock, organ dysfunction, requirement of ventilatory support) in very high risk febrile neutropenia patients managed with sepsis bundle based protocol. 2.To identify the association of baseline clinical factors, laboratory parameters, profile of infections and pattern of sepsis bundle compliance with 30 day mortality and other clinical outcomes in very high risk febrile neutropenia patients. Timepoint: 30days | — |
Countries
India
Contacts
Public ContactNarendran K
JIPMER
Outcome results
None listed