Health Condition 1: C01- Malignant neoplasm of base of tongue Health Condition 2: C04- Malignant neoplasm of floor of mouth Health Condition 3: C03- Malignant neoplasm of gum Health Condition 4: C050- Malignant neoplasm of hard palate Health Condition 5: C06- Malignant neoplasm of other and unspecified parts of mouth
Conditions
Interventions
Intervention1: No drug is administered: only saliva samples are obtained from the cancer patients
Control Intervention1: There is no comparator agent that is used: Only saliva samples are obtained fro
Sponsors
Tata Centre for Development at the University of Chicago
Eligibility
Inclusion criteria
Inclusion criteria: Case: Patients diagnosed of Oral Squamous Cell carcinoma, yet to undergo any therapeutic intervention
Exclusion criteria
Exclusion criteria: Patients diagnosed with any other disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Create a biomarker gene panel, based on previous work done in India and US, that contains the most commonly occurring mutations in OCSCC. Evaluate the diagnostic and prognostic accuracy of released tumor DNA (rtDNA) in saliva in patients with early stage OCSCC Timepoint: After about 6 months (April 2020) | — |
Secondary
| Measure | Time frame |
|---|---|
| To use rtDNA to detect genetic mutation that will enable early detection of oral cancerTimepoint: One year | — |
Countries
India, United States of America
Contacts
Public ContactMonica Charlotte Solomon
Manipal Academy of Higher Education
Outcome results
None listed