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Assessment of effectiveness and safety of minimal doses of propofol for sedation for MRI in children

EVALUATION OF SAFETY AND EFFICACY OF LOW DOSES OF PROPOFOL INFUSION FOR MAGNETIC RESONANCE IMAGING IN CHILDREN

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/11/022044
Enrollment
45
Registered
2019-11-18
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G80- Cerebral palsy Health Condition 2: K00-K95- Diseases of the digestive system Health Condition 3: M00-M99- Diseases of the musculoskeletal system and connective tissue Health Condition 4: G00-G99- Diseases of the nervous system Health Condition 5: G40- Epilepsy and recurrent seizures

Interventions

None listed

Sponsors

LOKMANYA TILAK MUNICIPAL MEDICAL COLLEGE AND LOKMANYA MUNICIPAL GENERAL HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. CHILDREN UNDERGOING MRI 2. AGE 1TO 9 YEARS 3. BOTH GENDERS 4. ASA STATUS (AMERICAN SOCIETY OF ANAESHESIOLOGISTS)- I AND II 5. ADEQUATE STARVATION AS PER GUIDELINES OF ASA

Exclusion criteria

Exclusion criteria: 1) ASA status: III and above. 2) Active Upper respiratory tract infection. 3) Severe cardiovascular or respiratory insufficiency 4) History of propofol allergy 5) Any contraindications for Dexmedetomidine and Ketamine administration 6) Anticipated difficult airway 7) Children having active seizures.

Design outcomes

Primary

MeasureTime frame
1. Awakening time 2. QUALITY OF SCAN 3. TOTAL DOSE OF PROPOFOLTimepoint: 1. AFTER STOPPING PROPFOL INFUSION 2. AFTER MRI SCAN COMPLETION 3. AFTER STOPPING PROPOFOL INFUSION

Secondary

MeasureTime frame
1. ANY ADVERSE EVENTS 2. ATTAIN SUCCESSFUL LEVEL OF SEDATION 3. DISCHARGE TIMETimepoint: 1. THROUGHOUT THE PROCEDURE. 2. TILL THE END OF MRI SCANNING 3. TIME AFTER AWAKENING TIME TO DISCHARGE OF CHILD

Countries

India

Contacts

Public ContactDR DEVENDRA THAKARE

LOKMANYA TILAK MUNICIPAL MEDICAL COLLEGE AND GENERAL HOSPITAL, SION, MUMBAI

devendra.thakare@gmail.com9892954998

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026