A study comparing the recovery and effect of three different doses of a drug in spinal anesthesia in patients undergoing female genital tract surgeries

INTRATHECAL 1% 2- CHLORPROCAINE FOR GYNECOLOGICAL DAY CARE SURGERY: A COMPARATIVE STUDY OF THREE DIFFERENT DOSES

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/11/022025

Enrollment

Registered

2019-11-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N90- Other noninflammatory disorders ofvulva and perineum

Interventions

Control Intervention1: Intethecal 1%, 2 Chlorprocaine 35mg: Spinal anesthesia will be performed in sitting position at L3-4 or L4-5 interspaces using 25 G whitacre spinal needle. 35mg 1% 2-chlorprocai

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 patients undergoing short gynecological surgeries under spinal anesthesia lasting less than 60 minutes

Exclusion criteria

Exclusion criteria: 1. Absolute contraindication to spinal anesthesia 2. Neurological diseases 3. Fluid restriction (cardiopulmonary or renal diseases) 4. Allergy or intolerance to local anesthetics

Design outcomes

Primary

Measure	Time frame
To study and compare the time required to meet eligibility for discharge from the hospital (modified post anaesthetic discharge scoring system) using three doses of 2- chlorprocaine i.e. 35mg, 40mg and 45mg.Timepoint: Sensory and motor blockade will be assessed every 3 mins till readiness of surgery is met and every15 mins for the first 60mins and every 30 mins thereafter till home discharge criteria is met.	—

Measure

Time frame

To study and compare the time required to meet eligibility for discharge from the hospital (modified post anaesthetic discharge scoring system) using three doses of 2- chlorprocaine i.e. 35mg, 40mg and 45mg.Timepoint: Sensory and motor blockade will be assessed every 3 mins till readiness of surgery is met and every15 mins for the first 60mins and every 30 mins thereafter till home discharge criteria is met.

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Secondary

Measure	Time frame
1.To study and compare the efficacy of three doses of 2- chlorprocaine i.e. 35mg, 40mg and 45mg in providing anesthesia for gynecological day care surgery. 2.To study the adverse effects of intrathecal 2- chlorprocaine if any. Timepoint: Heart rate, systolic and diastolic blood pressure and oxygen saturation will be recorded at baseline and immediately after spinal block, every 5 mins for the first 15 mins, every 30mins thereafter till discharge criteria is met. â?¢ 24 hrs after the procedure patient will be interviewed over the telephone for any adverse effects such as headache, vomiting or backache	—

Measure

Time frame

1.To study and compare the efficacy of three doses of 2- chlorprocaine i.e. 35mg, 40mg and 45mg in providing anesthesia for gynecological day care surgery. 2.To study the adverse effects of intrathecal 2- chlorprocaine if any. Timepoint: Heart rate, systolic and diastolic blood pressure and oxygen saturation will be recorded at baseline and immediately after spinal block, every 5 mins for the first 15 mins, every 30mins thereafter till discharge criteria is met. â?¢ 24 hrs after the procedure patient will be interviewed over the telephone for any adverse effects such as headache, vomiting or backache

—

Countries

India

Contacts

Public ContactJaya Choudhary

Medica Superspecialty Hospital,

jayachoudhry11@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026