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Evaluation of association between presence of Chromosomal Aberrations in different patterns of Orofacial Clefts.

Evaluation of the association between patterns of Chromosomal Abberations and Phenotypic presentation in subjects with Orofacial clefts - A Prospective Observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/11/021945
Enrollment
100
Registered
2019-11-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q35-Q37- Cleft lip and cleft palate

Interventions

Intervention1: nil: nil

Sponsors

Department of Oral and Maxillofacial surgery MGM dental college and hospital
Lead Sponsor
Department of Anatomy MGM Medical college and hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: participants with uni or bilateral, complete or incomplete cleft lip/ palate participants with sub mucous clefts participants with any tessier soft tissue or bony clefts participants with any combination of above clefts participants who may or maynot have been operated previously for the above conditions participants with orofacial clefts with or without systemic co morbidities participants with orofacial clefts with or without other congenital deformities prediagnosed syndromic patients with orofacial clefts

Exclusion criteria

Exclusion criteria: participants with features other than orofacial clefts participants not willing to participate in the study

Design outcomes

Primary

MeasureTime frame
Clinical features of Orofacial Clefts will be recorded. A thorough Systemic examination will be done to note the other systems if any involved with anomalies. Karyotyping will be done using the blood samples of the participants included in the study and a correlation will be done between the Phenotypic features and the chromosomal Aberrations if any.Timepoint: Day 1—

Secondary

MeasureTime frame
To correlate the Incidence of Orofacial Clefts with the Maternal history.Timepoint: Day 1;To determine the Incidence of Chromosomal Aberrations in Orofacial cleft patients. Timepoint: Day 1—

Countries

India

Contacts

Public ContactDr Gaurav Deshpande

MGM Dental college and hospital

srivalli.shrikanth@gmail.com9769088803

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026