FindTrial
Sign In

Is FFP really useful to prevent bleeding in patients with abnormal clotting planned for a procedure?

To study the utility of prophylactic fresh frozen plasma(FFP) transfusion for correction of coagulopathy prior to image guided catheter drainage for infected collections

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/11/021937
Enrollment
160
Registered
2019-11-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B99-B99- Other infectious diseases

Interventions

None listed

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients with plan for image guided catheter drainage procedure for infected collections

Exclusion criteria

Exclusion criteria: a) Thrombocytopenia defined by platelets b) Patients on medications like vitamin K antagonists, abciximab, tirofiban, ticlopidine or antiplatelet agents(ecospirin, clopidogrel) or heparin / anti Xa inhibitors. c) Known congenital or acquired bleeding diathesis or factor deficiencies (Haemophilia, Von Willebrand Disease) d) Contraindication to FFP transfusion (eg: fluid overload, anuria) e) Contraindication to image guided drainage due to anatomical reasons (proximity to vascular structures) or persistence of severe coagulopathy (INR > 3) after receiving weight based prophylactic FFP transfusion.

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of a weight based standard dose prophylactic FFP transfusion in non bleeding patients undergoing a image guided catheter drainage procedure for infected collection in correction of coagulopathy.Timepoint: To evaluate the efficacy of a weight based standard dose prophylactic FFP transfusion in non bleeding patients undergoing a image guided catheter drainage procedure for infected collection in correction of coagulopathy. This is by measuring the change in INR and PT post transfusion and monitoring the patient for upto 24 hours post procedure.—

Secondary

MeasureTime frame
To compare the rates of procedure related bleeding complications in patients without coagulopathy to those with coagulopathy prior to undergoing an image guided catheter drainage procedure for infected collections. To compare the bleeding complications in patients with coagulopathy who attain INR correction with those who do not attain significant INR correction with prophylactic FFP transfusion prior to undergoing an image guided catheter drainage procedure for infected collection. Timepoint: 24 hours—

Countries

India

Contacts

Public ContactPRADAKSHNA P

PGIMER

drarihantjain86@gmail.com9914208499

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026