Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: VAPcare medical device: We will connect the patients in the intervention group to VAPCare medical device with a disposable lumen (VAPLumen) that rides over the CASS ET tube with ports i
Sponsors
Dr D Vimal Bhardwaj
InnAccel Technologies Private Limited
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient aged more than or equal to 18 years, both the genders in the emergency and medical/surgical intensive care units. 2. Requiring artifical ventilation for more than 48 hours 3. Subject or legally authorized representative/patient relative willing to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1.A regular ET tube without continuous aspiration of subglottic secretion port 2. A previous diagnosis of a. Pulmonary tuberculosis b. Bronchopneumonia c. HIV d. Ventricular fibrillation e. Cardiac arrest f. Bleeding disorders/ on oral anticoagulants g. Pregnancy h. Head/ neck/ facial injuries 3. Tracheostomy at the time of admission 4. Patients enrolled for another clinical study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients developing ventilator associated pneumonia at the time of extubation or death or discharge against medical advice as defined by CDC, which is a Clinical suspicion of pneumonia in a patient mechanically ventilated for more than 48h and new or changing chest X-ray infiltrate with 2 out of following 3 clinical findings – new onset fever, leukocytosis, and purulent tracheal secretions with/without microbiological diagnosis.Timepoint: more than 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Adverse event rate 2.Mortality 3.Time to VAP rate 4.Duration of stay in the ICU/ hospitalization 5.Antibiotic usage 6.Microbiological assay (including oropharyngeal and subglottic secretions) 7.Cost effectiveness analysis 8.Volume of secretion collected in each region Timepoint: more than 48 hours | — |
Countries
India
Contacts
Public ContactDr Arjun Alva
Mazumdar Shaw Medical Center, Narayana Health city
Outcome results
None listed