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Comparison between Dexmedetomidine and Magnesium sulphate for heart rate, blood pressure,intra-operative bleeding in functional endoscopic sinus surgery

A Randomized Double Blind Interventional Study to Compare Hypotensive Properties of Dexmedetomidine Versus Magnesium Sulphate for Induced Hypotension During Functional Endoscopic Sinus Surgery at SMS Medical College Jaipur During 2018-19

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/11/021910
Enrollment
60
Registered
2019-11-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J339- Nasal polyp, unspecified

Interventions

Intervention1: hypotensive anaesthesia during functional endoscopic sinus surgeries: use of dexmedetomidine versus magnesium sulphate for hypotensive anaesthesia Intervention2: drugs magnesium sulphat

Sponsors

SMS Medical College Jaipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: body weight of 45 to 65 kg ASA grade 1 and 2 undergoing elective resection of nasal polyp (duration 60-70 minutes)

Exclusion criteria

Exclusion criteria: history of allergy to these drugs patients with pre existing bleeding and coagulation abnormalities history of hypertension, CAD, renal and hepatic dysfunction cerebral insufficiency patients not willing to participate in study orbital abscess CSF leak with or without CSF rhinorrhea

Design outcomes

Primary

MeasureTime frame
intraoperative SBP, DBP,MAP, HRTimepoint: base line after loading of study drug after induction 1 min after intubation 5 min after intubation 10 min 20 min 30 min 40 min 50 min 60 min 70 min—

Secondary

MeasureTime frame
ASSESMENT OF INTRAOPERATIVE BLEEDING BY SURGEON EMERGENCE TIME TIME TO FIRST RESCUE ANALGESIC DEMANDTimepoint: EVERY TEN MINUTES—

Countries

India

Contacts

Public ContactDr Jahnu Bhoj Nagal

SMS Medical College Jaipur

priyasingh.pgr@gmail.com9413901579

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026