To compare efficacy of low dose dexmedetomidine versus midazolam-fentanyl in eye surgery

A Comparative evaluation of dexmedetomidine versus midazolam-fentanyl for sedation in vitreoretinal surgery under peribulbar anaesthesia, a randomized, double-blind, prospective, interventional study at S.M.S. medical college and attached group of hospitals, Jaipur during 2018-2019 "

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/11/021892

Enrollment

Registered

2019-11-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H330- Retinal detachment with retinal break

Interventions

Control Intervention1: Intervention study: The dose of dexmedetomidine is 0.25 microgram/kg bodyweight.The frequency is one time loading dose and route of administration is intravenous and duration of

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2 patient undergoing vitreoretinal surgery upto 1 to 2 hrs duration

Exclusion criteria

Exclusion criteria: patient not willing in study patient on transquilizers, sedative drugs or psychitric medications patient with heart rate less than 60 bpm mentally sick patient patient with history of allergy to drug

Design outcomes

Primary

Measure	Time frame
both drug groups are eually efficacious in the studyTimepoint: after achieving desired sample size of 60 patients Approx 3 months duration	—

Secondary

Measure	Time frame
both drugs are eually efficaciousTimepoint: 3 months	—

Countries

India

Contacts

Public ContactRamakant Sharma

sms medical college hospital

purohitalaka@gmail.com8003399995

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026