Health Condition 1: D648- Other specified anemias
Conditions
Interventions
Intervention1: Allogeneic umbilical cord blood for transfusion in preterm neonates: Allogeneic umbilical cord blood will be collected from well term neonates born by elective caesarean delivery, proce
Sponsors
Intramural GATE Research fund from SRIHER
Eligibility
Inclusion criteria
Inclusion criteria: 1. For collection of UCB - Term (>=37 weeks gestation) infants delivered by elective caesarean section 2. For transfusion of UCB - Premature infants <1500 g birth weight requiring transfusion during the NICU stay
Exclusion criteria
Exclusion criteria: For collection of UCB 1. Mothers positive for HIV, HBsAg, HCV or VDRL 2. Mothers positive for unusual RBC antibodies screen 3. Mother who opt for cord blood banking 4. Maternal-fetal iso-immunization 5. Lack of consent For transfusion of UCB 1. UCB compatible with babyâ??s blood not available 2. Lack of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of red cell concentrates (RCC) transfusions in preterm infants that are covered by UCBTimepoint: Until discharge from the NICU | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Success rate of UCB collection after DCC (defined as absolute UCB volume â?¥ 25 mL) 2. Volume of UCB collected/volume of RCC obtained 3. Proportion of UCB units with satisfactory quality based on microbiological, hematological and biochemical parameters available until 21 days of storage.Timepoint: 21 days of storage (maximum) | — |
Countries
India
Contacts
Public ContactDr Thangaraj Abiramalatha
Sri Ramachandra Institute of Higher Education and Research Porur, Chennai
Outcome results
None listed