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Changes in bacterial flora of nose and throat before and after antibiotic therapy for acne

Changes in colonisation and antibiotic sensitivity pattern of Staphylococcus aureus from anterior nose and Streptococcus pyogenes from oropharynx before and after antibiotic therapy for acne: a hospital based prospective study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/11/021864
Enrollment
50
Registered
2019-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

None listed

Sponsors

GCS Medical college Hospital and Research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients greater than 14 years of age Patients clinically diagnosed as moderate to severe acne requiring oral antibiotics at the discretion of PI

Exclusion criteria

Exclusion criteria: Exclusion criteria: Patients lesser than 14 years of age Patients with concomitant systemic illness Patients with history of prior antibiotic therapy for acne or other illness in the last 3 months ï?· Patients in a health care related occupation ï?· Pregnant or lactating patients

Design outcomes

Primary

MeasureTime frame
1. to study the colonisation status of Staphylococcus aureus in anterior nose and Streptococcus pyogenes in oropharynx before and after oral antibiotics in acne patients 2. to study the antibiotic resistance patterns of Staphylococcus aureus in anterior nose and Streptococcus pyogenes in oropharynx before and after oral antibiotics in acne patientsTimepoint: End of duration of oral antibiotics on discretion of PI. There is no consensus on duration of oral antibiotic therapy and may extend from a period of 15 days to 6 months.

Secondary

MeasureTime frame
To study the correlation of colonisation and sensitivity patterns of proposed research bacteria in proposed body sites with type of antibiotic and duration of antibiotic use.Timepoint: End of duration of oral antibiotics on discretion of PI. There is no consensus on duration of oral antibiotic therapy and may extend from a period of 15 days to 6 months.

Countries

India

Contacts

Public ContactDr Nishi Trivedi

GCS medical College, hospital and research centre

nishi.trivedi04@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026