Health Condition 1: O721- Other immediate postpartum hemorrhage
Conditions
Interventions
Intervention1: Dose of oxytocin (1 out of 5): The various doses of oxytocin will include, 0.1 IU/kg/hr, or 0.15 IU/kg/hr, 0.2 IU/kg/hr, 0.25 IU/kg/hr, or 0.3 IU/kg/hr
Control Intervention1: nil: nil
Sponsors
University College of Medical Sciences and GTB Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Non-laboring parturients with no risk factors for increasing uterine atony, and posted for cesarean section under spinal block.
Exclusion criteria
Exclusion criteria: patient refusal, presence of labor, use of preoperative oxytocin for labor induction/augmentation,preterm gestational age, any risk factor for uterine atony including multiple gestation, polyhydramnios, macrosomia, history of PPH or previous uterine surgery or bleeding disorders, high parity, chorioamnionitis, uterine rupture, preeclampsia, and presence of abnormal placentation or uterine fibroids, contraindication to spinal block.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Side effects of oxytocin: a) Hypotension, b) Tachycardia, c) Lead II electrocardiographic ST-T changes, d) Nausea/vomiting, e) Flushing, and f) Chest pain. Timepoint: after start of oxytocin infusion till till end of surgery or prior to rescue bolus whichever is earlier. | — |
Primary
| Measure | Time frame |
|---|---|
| adequate uterine tone (assessed by the surgeon) Timepoint: 4 minutes after initiation of oxytocin, and entire subsequent time till skin closure. | — |
Countries
India
Contacts
Public ContactSURBHI TYAGI
University College of Medical Sciences and GTB Hospital
Outcome results
None listed