Health Condition 1: F102- Alcohol dependence
Conditions
Interventions
Intervention1: Astangalavana srikhandasava: 1. Astanga Lavana (B.R /Madatyaya/15-16, AFI Part-II, 7:3)
Dose : 3 gm twice daily
Dosage form : Choornam
Route of Administration : Oral
Time of Adm
Sponsors
Central Council For Research In Ayurvedic SciencesCCRAS
Eligibility
Inclusion criteria
Inclusion criteria: 1. Male Patient with age group of 18 to 60 years. 2. Patients who meet ICD-10 criteria for Alcohol dependence 3. Willing to participate for 3 months
Exclusion criteria
Exclusion criteria: 1. Patients suffering from any Organic brain disorder. 2. Patients suffering from major complications of Alcohol related disorders like Hepatitis, Cirrhosis of the liver etc. defined as 5 times increase in liver enzymes i.e. AST and ALT 3. Patients having the H/O concomitant other substance abuse except Nicotine/Caffeine 4. Patients suffering with other significant Systemic illness including Hyper Tension / Suicidal tendency 5. All psychiatry illness will be excluded by screening with MSE (Mental Status Examination)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| % days abstinent [Time frame:12weeks]- % days without any alcohol consumption over the treatment period assessed by Alcohol Time Line Follow Backup (TLFB), Urine Etg / Ets & Breath AnalyzerTimepoint: 3months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Any changes in Liver function tests i.e. GGT (Gamma Glutamyl Transferase) as biomarkers for recent drinking. 2.Any changes in Alcohol craving questionnaire (Pennââ?¬â?¢s craving scale, Annexure-III) scores from base line to end of treatment. 3.Improvement in Quality of life before and after treatment (WHOQOL-BREF) (Annexure-IV) Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactSrinibash Sahoo
Central Council for Research in Ayurvedic Sciences (CCRAS), New Delhi
Outcome results
None listed