Study to compare two different methods of wound closure following Total Knee Arthroplasty surgery

Randomized Control Trial to compare the efficacy of, and patient satisfaction levels, following skin closure with surgical staples vs 2-Octyl Cyanoacrylate together with a Self Ahering Mesh (Dermabond Prineo) after unilateral Primary Total Knee Arthroplasty surgery in patients with osteoarthritis of the knee

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/10/021778

Enrollment

300

Registered

2019-10-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Wound closure with 2-Octyl Cyanoacrylate together with a Self Ahering Mesh (Dermabond Prineo) after unilateral Primary Total Knee Arthroplasty surgery in patients with osteoarthritis of

Eligibility

Inclusion criteria

Inclusion criteria: -Patients who are 18 years of age and above, -Patients undergoing Primary Total Knee Arthroplasty surgery for osteoarthritis of the knee

Exclusion criteria

Exclusion criteria: -Age under 18 years -Known hypersensitivity to Dermabond Prineo Skin Closure System -Patients who have undergone any prior surgery to the knee planned for surgery -Patients with Inflammatory arthritis, crystalline arthropathy or secondary osteoarthritis of the knee

Design outcomes

Primary

Measure	Time frame
Efficacy of skin closure in both methods, to be assessed using POSAS clinician (observer) scaleTimepoint: 2 days, 2 weeks, 6 weeks. and 3 months post operatively	—

Secondary

Measure	Time frame
patient satisfaction level in both methods, to be assessed using POSAS (patient) scaleTimepoint: 2 days, 2 weeks, 6 weeks, and 3 months post operatively;readmission for wound related complicationsTimepoint: upto 3 months post operatively;wound dehiscenceTimepoint: upto 3 months post operatively;wound infectionTimepoint: upto 3 months post operatively	—

Countries

India

Contacts

Public ContactDr Apurve Parameswaran

Maxcure (Medicover) Hospitals, Madhapur

doctorapurve@gmail.com9585115242

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026