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Observing the correlation between factors affecting the response of macular edema due to retinal vein occlusion to first dose of anti VEGF injection

Factors influencing the first dose of anti VEGF in retinal vein occlusion induced macular edema

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/10/021774
Enrollment
127
Registered
2019-10-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H341- Central retinal artery occlusion

Interventions

Intervention1: Administration of intravitreal Anti - VEGF: The patient will be administered intravitreal bevacizumab under sterile precautions. 0.05ml of 1.25mg bevacizumab is dose that will be admini

Sponsors

Dr Shivraj Tagare
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Treatment naïve patients with RVO macular edema in any one eye, presenting to the outpatient department of the Retina Clinic at Aravind Eye Hospital, Pondicherry. Age above 18 years old.

Exclusion criteria

Exclusion criteria: Cases of RVO induced macular edema previously treated with intravitreal anti-VEGF bevacizumab injections, steroid injections or photocoagulation and macular edema due to any other cause. Patient opting for antiVEGF other than bevacizumab will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
1. Change in CRT/CMT recorded on an OCT. Timepoint: 1. Change in CRT/CMT recorded on an OCT after 1 month of intravitreal anti-VEGF injection

Secondary

MeasureTime frame
1. Change in SRF at the fovea on an OCT. 2. Betterment in visual acuity. 3. Correlation of the above with systemic factors and duration of disease. Timepoint: 1. Change in SRF at the fovea on an OCT after 1 month of giving intravitreal anti VEGF injection. 2. Correlation of the above with systemic factors and duration of disease.

Countries

India

Contacts

Public ContactDr Shivraj Tagare

Aravind Eye Hospital

manavi@aravind.org9884081417

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026