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A study to capture the patient characteristics, practices of treatment and observation measures used to maintain the blood pressure in patient presenting with early infection and low blood pressure.

Hemodynamic resuscitation and monitoring in early sepsis(HERMES Study)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/10/021726
Enrollment
500
Registered
2019-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R652- Severe sepsis Health Condition 2: R579- Shock, unspecified

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Indian Society of Critical Care Medicine
Lead Sponsor
Tata Memorial Hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients (>= 18 years old) 2. Presenting to ICU with suspected sepsis 3. Presence of hypotension (Systolic BP 90 mmHg / MAP >65mmHg on vasopressor

Exclusion criteria

Exclusion criteria: 1. Patient likely to be in shock due to reason other than sepsis (e.g. cardiogenic, hemorrhagic shock etc.) 2. Decision taken for not intubating / ventilating /aggressive resuscitation prior to ICU admission 3. Patient transferred from another hospital admitted for more than 7days 4. Patient transferred from another ICU

Design outcomes

Primary

MeasureTime frame
1.ICU Mortality 2.Sepsis resuscitation goals achieved in 1 hourTimepoint: Once after completion of study.

Secondary

MeasureTime frame
28-day mortalityTimepoint: Once after completion of study.;Hospital mortalityTimepoint: Once after completion of study.;Sepsis resuscitation goals achieved in 3 hourTimepoint: Once after completion of study.;Sepsis resuscitation goals achieved in 6 hourTimepoint: Once after completion of study

Countries

India

Contacts

Public ContactDrSheila Nainan Myatra

Tata Memorial Hospital

sheila150@hotmail.com9820156070

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026