Evaluation of changes in extraction socket of tooth after filling with tooth powder mixed with blood derived product

Clinical, Histomorphometric and 3-Dimensional Cone Beam Computed Tomographic Analysis of Autogenous Tooth Bone Graft Mixed with Injectable Platelet Rich Fibrin for Ridge Preservation

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/10/021714

Enrollment

Registered

2019-10-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R69- Illness, unspecified

Interventions

Intervention1: Autogenous tooth bone graft mixed with injectable platelet rich fibrin: Autogenous tooth bone graft particles will be filled in the extraction socket followed by injection of 5 ml of in

Eligibility

Inclusion criteria

Inclusion criteria: b) Patients who have a clinically determined need for extraction of single rooted non-molar tooth (root or crown fractures, non-restorable caries and residual roots). followed by an implant supported restoration c) Patients who will be available for further follow up. d) Adequate restorative space for implant-supported restoration e) Presence of at least one tooth on each side to the tooth to be extracted. f) = 10-mm distance of alveolar bone crest from the base of the socket. g) Root location and angulation that would be consistent with the subsequent implant placement.

Exclusion criteria

Exclusion criteria: a) Inability or anticipated failure to maintain adequate oral hygiene b) Pregnant or lactating moth¬ers c) Patients with other systemic conditions (uncontrolled diabetes, unstable bleeding disorders, active infectious diseases; hepatitis, tuberculosis, HIV etc.) that could affect the healing ability of wound. d) Mental disabilities that may hinder participation. e) Active immunosuppressive therapy, cancer therapy and/or radiation to the oral cavity within the past 6 months f) Patients with acute dental infection of bone and ankylosed teeth. g) Conditions/medications contraindicated for bone regeneration (e.g. methotraxate, cyclosporine A, steroids, bisphosphonates). h) Multirooted teeth because of the potential for presence of interradicular bone that might be harvested as part of the core biopsy procedure. i) Loss of more than 50% of buccal plate at the time of extraction

Design outcomes

Primary

Measure	Time frame
Postextraction dimensional and histologic changes in grafted socketsTimepoint: 4 months	—

Secondary

Measure	Time frame
Maximum insertion torque value during implant placement and radiographic bone densityTimepoint: 4 months	—

Countries

India

Contacts

Public ContactVikender Singh

All India Institute of Medical Sciences

vikenderyadav@gmail.com8800798248

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026