Health Condition 1: null- Pediatric Irritable Bowel syndrome
Conditions
Interventions
Intervention1: Psyllium husk: Dietary fiber
6 g/day for 4 -12 years age and 12 g for 13 to 18 years
Dosing : Twice daily in 2 divided doses
Route : Oral
Duration : 4 weeks
Control Intervention1:
Sponsors
Jagadeesh Menon V R
Eligibility
Inclusion criteria
Inclusion criteria: Criteria of Pediatric IBS ROME 4
Exclusion criteria
Exclusion criteria: Children with IBS already on drug therapy or suffering from chronic diseases including, cardiac, renal and hepatic, failure to thrive, bronchial asthma, prior GI surgeries, malignancies, celiac disease, inflammatory bowel disease, cystic fibrosis, anatomical malformations of the gut, immune deficiencies, hypothyroidism, neurological and muscle diseases, and anatomical causes of bowel dysfunction will ruled out by clinical, laboratorial and radiological investigations. Child not on antibiotic therapy for atleast 4 weeks prior to enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom response to Psyllium VERSUS placebo as per IBS Severity scoring systmemTimepoint: symptom response after 4 weeks of starting medications | — |
Secondary
| Measure | Time frame |
|---|---|
| IL 6 and IL 10 levels at baseline and 4 weeks post intervention in the two drug limbsTimepoint: 4 WEEKS;Small intestinal bacterial overgrowth and its response to therapyTimepoint: 4 weeks | — |
Countries
India
Contacts
Public ContactJagadeesh Menon
PGIMER, Chandigarh
Outcome results
None listed