A study to evaluate the safety profile of phacoemulsification on corneal endothelium in different grades of cataract

A study to evaluate the corneal endothelium in different grades of cataract after phacoemulsification

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/10/021696

Enrollment

195

Registered

2019-10-17

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H251- Age-related nuclear cataract

Interventions

Intervention1: Phacoemulsification cataract surgery: 1.All the surgeries will be performed by single surgeon in order to minimize bias. 2.After application of wire speculum the incision will be given

Eligibility

Inclusion criteria

Inclusion criteria: Patients with senile cataract undergoing phacoemulsification at Regional Institute of Ophthamalology, Pt. B. D. Sharma PGIMS, Rohtak.

Exclusion criteria

Exclusion criteria: 1. Patient with history of diabetes 2. Previous corneal disease, corneal trauma, intraocular surgery 3. Pseudoexfoliation syndrome 4. Co-existent glaucoma 5. Corneal endothelial dystrophy 6. Intraoperative complications- PCR, vitreous loss, iris trauma, descemetâ??s detachment 7. Uveitis 8. Anterior chamber depth less than 2 mm 9. Patient refusing to give consent for the study

Design outcomes

Primary

Measure	Time frame
Status of corneal endothelium in terms of endothelial cell loss, endothelial cell morphology and corneal thickness before and after phacoemulsification using specular microscopy in different grades of cataract.Timepoint: Data will be recorded before surgery,post-op day 1, 1st week post-operatively and 4th week post-operatively. After the collection and compilation of data, appropriate statistical test will be used to analyse the results.	—

Measure

Time frame

Status of corneal endothelium in terms of endothelial cell loss, endothelial cell morphology and corneal thickness before and after phacoemulsification using specular microscopy in different grades of cataract.Timepoint: Data will be recorded before surgery,post-op day 1, 1st week post-operatively and 4th week post-operatively. After the collection and compilation of data, appropriate statistical test will be used to analyse the results.

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Secondary

Measure	Time frame
Status of corneal endothelium in terms of endothelial cell loss, endothelial cell morphology and corneal thickness before and after phacoemulsification using specular microscopy in different grades of cataract.Timepoint: Data will be recorded before surgery,post-op day 1, 1st week post-operatively and 4th week post-operatively. After the collection and compilation of data, appropriate statistical test will be used to analyse the results.	—

Measure

Time frame

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Countries

India

Contacts

Public ContactDr Apoorva Goel

Regional Institute of Ophthalmology, PGIMS, Rohtak

goelapoorva94@gmail.com8395975985

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026