Health Condition 1: M179- Osteoarthritis of knee, unspecified
Conditions
Interventions
Intervention1: Osteo-arthritis nosode in centesimal potencies: Osteo-arthritis nosode in centesimal potencies, as decided appropriate to the case or condition. In centesimal scale, each dose shall con
dosage and repetition depending upon the individual requirement of the cases. The medicines will be procured from a Good Manufacturing Practice (GMP)-certified firm. General management will include ic
Sponsors
D N De Homoeopathic Medical College Hospital Govt of West Bengal
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 35-70 years 2. Both sexes 3. Diagnosed knee osteoarthritis as per American College of Rheumatology (ACR) clinical/radiographic classification criteria: a) Knee pain b) At least 1 of 3: age more than 50 years, stiffness less than 30 min, and crepitus on knee motion c) Osteophytes on knee x-ray 4. Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of osteoarthritis, provided the medications are stopped completely at least 2 weeks prior study entry 5. Literate patients; can read Bengali, Hindi or English 6. Providing written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( >12°), evidenced by imaging or other evidences and requiring surgical intervention 2. Non-ambulant patients 3. Self-reported joint disorders other than osteoarthritis (e.g., inflammatory joint disease, specific arthropathy, hyperuricaemia and/or gout, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs) 4. Intra-articular injections within 2 weeks before study entry 5. Transplanted knees 6. Recent significant knee surgery within last 6 months 7. Patients who are too sick for consultation 8. Unwilling to take part and not giving consent to join the study 9. Unable to read patient information sheet 10. Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life 11. Pregnancy and lactation 12. Substance abuse and/or dependence 13. Self-reported immune-compromised state, and 14. Undergoing homeopathic treatment for any chronic disease within last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee injury and Osteoarthritis Outcome Score (KOOS)Timepoint: At baseline, every month up to 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| EQ-5D-5L questionnaireTimepoint: At baseline, every month up to 3 months;Frequency of add-on Paracetamol and/or NSAIDs (oral/topical) useTimepoint: At baseline, every month up to 3 months | — |
Countries
India
Contacts
Public ContactShyamal Kumar Mukherjee
D. N. De Homoeopathic Medical College & Hospital, Govt. of West Bengal
Outcome results
None listed