Health Condition 1: S721- Pertrochanteric fracture
Conditions
Interventions
Intervention1: Intravenous tranexamic acid: 2 doses of slow infusion of TXA 10 mg per kg body weight, 10 minutes prior to incision and at two hours from first dose
Intervention2: Local tranexamic acid
Sponsors
Sri Sathya Sai Institute of Higher Medical Sciences Prasanthigram
Eligibility
Inclusion criteria
Inclusion criteria: 1. Evans types 1 and 2 2. Internal fixation by Dynamic Hip Screw
Exclusion criteria
Exclusion criteria: 1. Fractures managed with cephalomedullary nails or other surgical modalities. 2. Use of antiplatelet agents or anticoagulants at the time of admission 3. History of cardiac disease or cerebrovascular diseases 4. Documented allergy to TXA 5. History of DVT or pulmonary embolus 6. Hepatic dysfunction 7. Renal dysfunction 8. Derangement of blood coagulation parameters 9. History of malignancy
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Any complicationsTimepoint: 6 weeks from surgery;No. of packed cells transfused postoperativelyTimepoint: 6 weeks;Total, visible and hidden blood lossesTimepoint: 5th postoeprative day | — |
Primary
| Measure | Time frame |
|---|---|
| Hb fall on day 5 after accounting for intraoperative and post-operative transfusionTimepoint: Hb fall on day 5 after accounting for intraoperative and post-operative transfusion | — |
Countries
India
Contacts
Public ContactKoushik Narayan Subramanyam
Sri Sathya Sai Institute of Higher Medical Sciences - Prasanthigram
Outcome results
None listed