Health Condition 1: E15-E16- Other disorders of glucose regulation and pancreatic internal secretion
Conditions
Interventions
Intervention1: Not applicable: Not applicable
Control Intervention1: Not applicable: Not applicable
Sponsors
Christian Medical College Vellore
Eligibility
Inclusion criteria
Inclusion criteria: 1.Indian nationals 2.Dysglycemia as per the following definition: -Impaired fasting glucose (fasting plasma glucose 100-125 mg/dl on a 75 g oral glucose tolerance test) OR -Impaired glucose tolerance (2 hour plasma glucose 140 - 199 mg/dL on a 75 g oral glucose tolerance test) OR -Impaired fasting glucose and impaired glucose tolerance on a 75 g oral glucose tolerance test OR -HbA1C 5.7-6.4% (with or without the above conditions) 3.Certified medically fit to donate a kidney by the treating nephrologist after completing all investigations 4.Provide written, informed consent for inclusion in the study
Exclusion criteria
Exclusion criteria: 1.Age > 60 years 2.Prospective kidney donors with haemoglobinopathies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of diabetes defined as -fasting plasma glucose â?¥126 mg/dL or 2 hour post prandial plasma glucose 200 mg/dL or both on a 75 g oral glucose tolerance test OR -HbA1C â?¥ 6.5% OR -Participant started on antidiabetic therapyTimepoint: 2,4,6,8,10 years | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of IFG and IGT on peri-nephrectomy complicationsTimepoint: 2,4,6,8,10 years;Effect of IFG and IGT on post donation renal function (CKD EPI eGFR, 24 hour urine protein) Timepoint: 2,4,6,8,10 years;Risk factors for diabetes Timepoint: 2,4,6,8,10 years | — |
Countries
India
Contacts
Public ContactAnna T Valson
Christian Medical College, Vellore
Outcome results
None listed