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use of different anesthetic solutions in providing pain relief during root canal treatment

Effect of varying concentrations of epinephrine in 2% lidocaine on the anesthetic success rate of intraligamentary injections in patients with symptomatic irreversible pulpitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/10/021593
Enrollment
90
Registered
2019-10-10
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 4% Articaine: The patients receive intraligamentary injections of 4% articaine with 1 : 100 000 epinephrine Control Intervention1: 2% lidocaine: The patients receive intraligamentary in

Sponsors

Faculty of Dentistry self funded
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: the inclusion criteria will be carious exposed symptomatic mandibular molars; a positive and prolonged response to thermal tests and electric pulp test; a vital coronal pulp on access opening; American Society of Anesthesiologists class I or II medical history; and the ability to understand the use of pain scales.

Exclusion criteria

Exclusion criteria: Exclusion criteria will be known allergy or contraindications to any content of local anesthetic solution, patients who are pregnant or breast-feeding, a history of known or suspected drug abuse, and patients taking any drugs which could affect the pain perception. Patients having active pain in more than 1 teeth will be excluded from the study. Teeth with fused roots, radiographic evidence of an extra root, large restorations with overhanging margins, gingival inflammation, full crowns or deep periodontal pockets will also be excluded.

Design outcomes

Primary

MeasureTime frame
The primary outcome was defined as ââ?¬Å?success or failureââ?¬? which was indicated as the ability to undertake pulp access and canal instrumentation with no or mild pain.Timepoint: The primary outcome will be evaluated at the baseline

Secondary

MeasureTime frame
The secondary outcome was the evaluation of heart rate (number of heart beats per minute) after injections.Timepoint: Just after giving intraligamentary injections

Countries

India

Contacts

Public ContactVivek Aggarwal

Faculty of Dentistry

drvivekaggarwaldrive@gmail.com09818188358

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026