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A comparative study of Fentanyl versus Dexmedetomidine as adjuvants to Ropivacaine in Epidural anesthesia in surgeries below the umbilicus for post operative pain

A prospective randomized double blind comparative study of Fentanyl versus Dexmedetomidine used as adjuvants to Ropivacaine in Epidural anesthesia in infra umbilical surgeries for post operative analgesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/10/021565
Enrollment
60
Registered
2019-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D28- Benign neoplasm of other and unspecified female genital organs Health Condition 2: K35-K38- Diseases of appendix Health Condition 3: N40-N53- Diseases of male genital organs Health Condition 4: K40-K46- Hernia Health Condition 5: C40-C41- Malignant neoplasms of bone and articular cartilage Health Condition 6: C51-C58- Malignant neoplasms of female genital organs Health Condition 7: C60-C63- Malignant neoplasms of male genital organs Health Condition 8: M15-M19- Osteoarth

Interventions

Intervention1: Ropivacaine with Fentanyl: Injection Ropivacaine 0.75% 17ml + Injection Fentanyl 1mcg/kg , injected intermittently through the epidural catheter over 3minutes, top up doses for pain po

Sponsors

Bangalore Medical College and Research Institute
Lead Sponsor
Department of Anesthesiology
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients who are willing to give informed written consent 2)Patients of 18-60 years of either sex 3)Patients with height >140 centimetres and weight >45 kilograms upto 90 kilograms 4)ASA grade I and II 5)Elective infra umbilical surgeries

Exclusion criteria

Exclusion criteria: 1)Patients refusing to give informed written consent 2)Patients with any contraindication for neuraxial blockade 3)Allergy to study drug 4)Patients on alpha-2 antagonist treatment and on anticoagulants 5)Patients posted for lower segment caesarean section

Design outcomes

Primary

MeasureTime frame
Total dose consumption of local anesthetic usedTimepoint: Over 24 hours Post operative period

Secondary

MeasureTime frame
First request for post operative analgesiaTimepoint: post operative period;SedationTimepoint: Intraoperative period Post operative perod upto 24 hours

Countries

India

Contacts

Public ContactDR RAMESH R

BANGALORE MEDICAL COLLEGE AND RESEARCH INSTITUTE

rameshrevanna@yahoo.co.in9844837939

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026