Health Condition 1: E40-E46- Malnutrition Health Condition 2: E559- Vitamin D deficiency, unspecified
Conditions
Interventions
Intervention1: Daily versus monthly oral vitamin D3 in equivalent doses for treatment of symptomatic vitamin D deficiency in infants:A Randomized Controlled Trial.: the selected subjects will be rando
Sponsors
Lady Hardinge Medical College Associated Hospital New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: All infants (upto 12 months age) presenting with symptoms compatible with vitamin D deficiency and documented to have serum vitamin D levels infants with - Hypocalcemic seizures - Clinically & radiologically diagnosed rickets
Exclusion criteria
Exclusion criteria: -Infant with non â??nutritional rickets -Infants having known comorbidities affecting vitamin D metabolism like: Diarrhea and other mal-absorption syndromes, hepatic disorder , renal disorder, infants on concomitant anticonvulsant therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of two treatment regimens will be assessed comparing the proportion of subjects in in the 2 groups with -Complete normalisation of radiological score for healing of rickets, - Normalisation of serum ALP, calcium, Phosphate, PTH & serum 25(OH) D Timepoint: at one month, two month and three month after starting treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| The safety of the therapy will be estimated by measuring prevalence of the following Hypercalcemia, hypercalciurea and Hypervitaminosis DTimepoint: at 1month , 2 months and 3 months after starting treatment | — |
Countries
India
Contacts
Public ContactAnupriya
Kalawati Saran Childrens Hospital. New Delhi
Outcome results
None listed