Health Condition 1: I39- Endocarditis and heart valve disorders in diseases classified elsewhere
Conditions
Interventions
Intervention1: iv inj nalbuphine: 30 patients will receive inj. nalbuphine 0.2mg/kg iv slowly 5 minutes before induction and thereafter repeated if BIS SCORE more than 60 during surgery.
Interventi
Sponsors
Department of anesthesiologySMS medical college jaipur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Either sex 2. Age group 18-65yrs 3 .Body weight 40-70kg 4. ASA Grade II &lll 5. Scheduled for cardiac surgery on cardiopulmonary bypass
Exclusion criteria
Exclusion criteria: 1. Patients not willing to participate in study 2. Uncooperative patients 3. Patients with history of drug allergy 4. Patients with pre-existing, Asthma, Renal or Hepatic dysfunction 5. Morbid obese patient 6. Pregnancy/Lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare hemodynamic variables from baseline at different time interval in both groups. Heart rate Systolic blood pressure Diastolic blood pressure Mean Arterial Pressure central venous pressure Timepoint: Data will be recorded baseline (before induction), just after intubation, 5 min and 15 min, 30 min after intubation nd after that 5 min before going on pump, 5 min after going on pump, every 30 min till shifted to icu. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To asses and compare BIS guided total requirement of analgesic drug in bothgroups 2.To assess and compare the time required for first rescue analgesic in both group in postoperative period after extubation according to VAS score. 3.To compare side effects and complications of both drugs. Timepoint: After extubation ,post operative analgesia evaluted by visual analogue scale (VAS)in every 30 mins till vas more then 3 | — |
Countries
India
Contacts
Public ContactDR SAURABH KUMAR SHARMA
sms medical college jaipur
Outcome results
None listed