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Personalized Treatment for Blood Cancer

Clinical Pharmacogenomics study of Imatinib in Chronic Myeloid Leukaemia patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/10/021533
Enrollment
200
Registered
2019-10-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C921- Chronic myeloid leukemia, BCR/ABL-positive

Interventions

None listed

Sponsors

R Saravanabhavan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are already under the treatment for Chronic Myeloid Leukaemia Patients of both male and female sexes are included Age range of the patients should be 18 to 85 should have completed 18 years before taking part in the study Patients in any stage of the CML are included

Exclusion criteria

Exclusion criteria: Patients with concurrent malignancies other than CML 2. A serious uncontrolled medical disorder that would impair the ability of the subjects to receive therapy. Hence, patients with any of the following diseases other than CML who are considered not suitable by the physician will not be recruited for this research project: Cardiovascular Disease Fluid Retention, Bone Marrow suppression Gastrointestinal Disorders Hepatic Impairment Hypothyroidism Renal Impairmen Patients treated with any other chemotherapeutic drugs in addition to imatinib Female patients who are pregnant Patients who have not completed 18 years of age

Design outcomes

Primary

MeasureTime frame
Identification of SNPs Genetic Biomarkers that are associated with the Imatinib clinical response Toxicity and Resistance Timepoint: 3rd month 6th month 1 year

Secondary

MeasureTime frame
Identification of SNPs Genetic Biomarkers that are associated with the Imatinib ResistanceTimepoint: Third Month 6th month one year

Countries

India

Contacts

Public ContactR Saravanabhavan

Vels University

mailshanmuga@gmail.com9626222116

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026