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Comparative study of brain function monitoring and proactive brain protection for neurologic outcome in patients undergoing brain aneurysm surgery

Comparative study of SSEP/EEG based cerebral ischemia monitoring and preemptive anaesthetic neuroprotection for neurological outcome in patients undergoing temporary clipping during intracranial aneurysm surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/10/021496
Enrollment
60
Registered
2019-10-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G94- Other disorders of brain in diseases classified elsewhere

Interventions

Intervention1: Group N: Group N: Providing Neuroprotection before temporary clipping by using Propofol to achieve burst suppression based on EEG monitoring. Intervention2: Group N: Providing Neuropr

Sponsors

National Institute of Mental Health and Neurosciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) Patients requiring temporary parent vessel occlusion, during surgical clipping of ruptured intracranial aneurysm of anterior circulation

Exclusion criteria

Exclusion criteria: a) Previous intracranial or spinal surgery b) Previous stroke or coronary event

Design outcomes

Primary

MeasureTime frame
a) Difference of incidence of new onset neurological deficit within 24 hours postoperatively, between the groupsTimepoint: Within 24 hours after surgery—

Secondary

MeasureTime frame
a) Difference of neurological outcome between the groups as measured by Extended Glasgow Outcome Scale (GOSE)Timepoint: 3 months, 6months—

Countries

India

Contacts

Public ContactGopalakrishna K N

National Institute of Mental Health and Neurosciences

gops868@gmail.com9916469626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026