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A clinical trial to study the effect of injection cisatracurium with or without magnesium pretertment in cardiopulmonary by pass surgery

COMPARISON OF THE EFFECT OF CISATRACURIUM WITH OR WITHOUT MAGNESIUM PRETREATMENT ON NEUROMUSCULAR BLOCKADE AND HEMODYNAMICS IN CARDIAC SUEGERY PATIENTS ON CARDIOPULMONARY BYPASS AT SMS MEDICAL COLLEGE (2018-2019)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2019/09/021475
Enrollment
60
Registered
2019-09-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: INJECTION CISATRACURIUM WITH MAGNESIUM: â??-Pretreatment with mgso4(50mg/kg BW in 100ml NS in 10 mints before induction ) and receive general anesthesia (GA) and muscle relaxant inject

Sponsors

Department of Anaesthesiology Medical CollegeJaipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA Grade 2 and 3 2. Patients with Mallampati Grade 1 and 2 3. Age between 20-60 years 4.cardiac Surgery patient on cardiopulmonary bypass 5 body weight 45-65

Exclusion criteria

Exclusion criteria: Weight deviation >20%from ideal body weight. Major hepatic ,renal,pulmonary and neuromuscular disease.hypothroidism or hyperthroidism Preoperative medication within last 72hr that might interfere with neuromuscular transmission. More than 3 attempts of intubation.

Design outcomes

Primary

MeasureTime frame
1-To assess and compare Intubating conditions and timing of intubation in seconds. 2-To assess and compare clinical duration of blockade of intubating dose of cis-atracurium Timepoint: 1-To assess and compare Intubating conditions and timing of intubation in seconds. 2-To assess and compare clinical duration of blockade of intubating dose of cis-atracurium—

Secondary

MeasureTime frame
1-Hemodaynamics variable(HR SBP MAP DBP). 2- Side effect if any Timepoint: data recorded at the time of intubation then every 15 minutes—

Countries

India

Contacts

Public ContactDR Anjum saiyed

S.M.S. MEDICAL COLLEGE JAIPUR

dranjumsaiyed@gmail.com9214021930

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026