Health Condition 1: S06- Intracranial injury
Conditions
Interventions
Intervention1: Thiamine & Ascorbic acid adjuvant therapy: All patients with head injury admitted to the Trauma centre ICU with primary neurosurgical diagnosis shall be classified based on their Glasgo
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients (18 – 60 yrs) with an ASA physical status I and II of either sex 2. History of Traumatic Brain Injury 3. Patients getting admitted to the Trauma ICU with head injury, whether operated or not
Exclusion criteria
Exclusion criteria: 1. Patients below 18yrs or above 60yrs 2. Pregnant women 3. Patients with G-6-PD deficiency 4. Patients with a history of nephrolithiasis/Gout/renal disorders/chronic renal failure 5. Immunocompromised patients (taking >10 mg of prednisone equivalent per day for at least 2 weeks, receiving cytotoxic therapy or diagnosed with an acquired immunodeficiency syndrome) 6. Chronic alcoholics/liver disease patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MortalityTimepoint: 28 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Days of ICU stay Serum Lactate levels WBC counts Neurological scoring trends via GCS & FOUR scoring Superinfection Number of ventilator daysTimepoint: 15 days | — |
Countries
India
Contacts
Public ContactDr Ghanshyam Yadav
Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh
Outcome results
None listed