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Comparison of antibacterial effect of double antibiotic and triple antibiotic paste in root canals of primary teeth.

Evaluation and comparison of antimicrobial effect of double antibiotic paste and triple antibiotic paste as an intracanal medicament on selected pathogens from pulpectomy Indicated deciduous teeth-An Ex-vivo study - DAP/TAP

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/09/021459
Enrollment
20
Registered
2019-09-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 1) Double antibiotic paste mixed in propylene glycol 2) Triple antibiotic paste mixed in propylene glycol : To assess microbial flora root canal samples will be taken before and after p

Sponsors

Lipika Shivrain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients reporting to the department O.P.D 2 Age group 3-9 years 3 Teeth indicated for pulpectomy 4 Patient should be healthy 5 Patient willing to participate and fill the consent form 6 Deciduous molars with almost 2/3 of root present and no previous pulp therapy

Exclusion criteria

Exclusion criteria: 1 Patients not willing to participate 2 Teeth indicated for other than pulpectomy procedures 3 Teeth with more than 2/3 of root resorbed 4 Patients under any antibiotic therapy 5 Patient with systemic disease and any history of drug allergy

Design outcomes

Primary

MeasureTime frame
-Double antibiotic paste will have significantly higher antimicrobial effect on specific microorganisms than Triple antibiotic paste when used as an intracanal medicament in pulpectomy indicated primary teeth. -Triple antibiotic paste will have significantly higher antimicrobial effect on specific microorganisms than Double antibiotic paste when used as an intracanal medicament in pulpectomy indicated primary teeth. Timepoint: 7 days

Secondary

MeasureTime frame
1. To evaluate the antibacterial activity of intracanal medicaments a) Group A ââ?¬â?? Double antibiotic paste b) Group B ââ?¬â?? Triple antibiotic paste 2. To identify selected microorganisms (Streptococcus mutans, Streptococcus salivarius & Enterococcus faecalis) from root canals of infected deciduous teeth by culturing them in a specific media.Timepoint: 10/2/2020

Countries

India

Contacts

Public ContactLipika Shivrain

Maharishi Markandeshwar College Of Dental Science And Research

hpsumasogi@gmail.com8197793383

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026