It is a study to compare the effectiveness of two anaesthesia techniques in reducing postoperative nausea and vomiting in female patients undergoing laparoscopic surgery using propofol in one and combination of propofol and sevoflurane as maintenance agents in another

Comparative study to evaluate propofol and combination of propofol and sevoflurane as maintenance agents in reducing postoperative nausea and vomiting in female patients undergoing laparoscopic surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2019/09/021449

Enrollment

Registered

2019-09-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K808- Other cholelithiasis

Interventions

Intervention1: maintenance of anaesthesia with propofol: maintenance of anaesthesia with propofol infusion alone by titrating the rate of infusion according to BIS Control Intervention1: Maintenance o

Eligibility

Inclusion criteria

Inclusion criteria: female patients belonging to American society of anaesthesiologists (ASA) physical status I or II, scheduled for laparoscopic surgery and requiring endotracheal intubation will be included in the study

Exclusion criteria

Exclusion criteria: Patients with: 1. Obesity (BMI >30kg/m.m) 2. history of nausea and vomiting or motion sickness 3. history of gastro-esophageal reflux disease 4. history of anti-emetic use in last 2 weeks before surgery 5. history of smoking or alcohol use 6. refusal to participate in study will be excluded from the study

Design outcomes

Primary

Measure	Time frame
comparison of propofol alone and combination of propofol and sevoflurane as maintenance agents in reducing postoperative nausea and vomitingTimepoint: 30mins, 60mins, 90mins, 120mins, 6hrs, 12hrs, 18hrs, 24hrs postoperatively	—

Secondary

Measure	Time frame
incidence of postoperative nausea and vomiting and requirement of rescue antiemeticTimepoint: 30mins, 60mins, 90mins, 120mins, 6hrs, 12hrs, 18hrs, 24hrs postoperatively	—

Countries

India

Contacts

Public Contactkhushboo

Pt. BDS University of health sciences , rohtak

khushbooknd6@gmail.com8295749959

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026