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Therapy for Sensory Deficit in Patients with half-side body paralysis

Neuralplasticity-based Sensory-Rehabilitation Protocol in Post-Stroke Hemiparesis - NEPSER

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/09/021442
Enrollment
122
Registered
2019-09-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I630- Cerebral infarction due to thrombosis of precerebral arteries Health Condition 2: I611- Nontraumatic intracerebral hemorrhage in hemisphere, cortical

Interventions

Intervention1: NEuroplasticity-Principles-based SEnsory-Rehabilitation (NEPSER): Protocol is based on the key principles of neuroplasticity established in relation to the rehabilitation of stroke subj

Sponsors

Indian Council of Medical Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Hemiparesis (right or left) (as assessed by Fugl-Meyer assessment62 upper extremity subsection: 0 to 66) First episode of unilateral stroke (as defined by WHO) Ischemic or hemorrhagic stroke 1 to 12 months after the stroke onset Impaired or more sensory deficit of any of the sensory modalities ( Normal visual abilities (with or without glasses)

Exclusion criteria

Exclusion criteria: Receptive communication or other language disorder (which could interfere with the assessment and treatment process) Contractures and deformities of hand / finger Use of hand splinting or orthosis Complex regional pain syndrome Severe cognitive or perceptual deficit Concomitant medical illness Cardiovascular instability: resting systolic blood pressure >200mmHg and resting diastolic blood pressure >100 mmHg Pregnancy Renal infection or failure Severe depression (Beck depression inventory > 30) Diabetic or any other neuropathy Skin disorder Peripheral nerve injury of either of the upper limbs

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment, Nottingham Sensory Assessment (Erasmus MC modification of the revised version)Timepoint: Baseline, 8-week, 12-week

Secondary

MeasureTime frame
Semmes Weinstein Monofilament, Two-Point Discrimination,3. Modified Rankin scaleTimepoint: Baseline, 8-week, 12-week

Countries

India

Contacts

Public ContactDr Kamal Narayan Arya

Pt. Deendayal Upadhyaya National Institute for Persons with Physical Disabilities

kamalnarya@yahoo.com011-23232403

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 24, 2026