Health Condition 1: Q203- Discordant ventriculoarterial connection
Conditions
Interventions
Intervention1: HTK cardioplegia solution: Dose:30ml/kg
Frequency : One dose through Route :into aorta
Duration: only once for entire duration of surgery
Control Intervention1: del Nido cardioplegia
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: children in the above mentioned age group undergoing elective Arterial Switch Operations
Exclusion criteria
Exclusion criteria: 1. Patients for which consent not provided by parents for inclusion in study. 2. Patients with other associated illnesses 3. Preoperative neurological defects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a) Cardiac index with the use of the 2 cardioplegia solutions in operation theatre after coming off CPBTimepoint: in ICU after 4hours, 12 hours, 24 hours and 48 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| a)Diffrences in inotropic scores in two group at 24,48,72 and 96 hours. bTo assess and compare the levels of inflammatory markers before and after cardiopulmonary bypass with the use of these cardioplegia solution. d)To assess and compare the ultra structural changes in the myocardium after cardioplegia. Timepoint: post op 24hours, 48 hours, 72 hours, 96hours | — |
Countries
India
Contacts
Public ContactDr Srikant sharma
AIIMS
Outcome results
None listed