None listed
Conditions
Interventions
None listed
Sponsors
Dr Devadarshini Sahoo
Eligibility
Inclusion criteria
Inclusion criteria: Pregnant female of age 18 â?? 40 years Gestational age Having at least any one of the high risk feature for developing GDM like Overweight (BMI more tham equal to 23 kg/m2) Family history of type 2 DM Polycystic ovary syndrome Previous history of macrosomic ( >4 kg) or large for gestational age infant (weight > 90 percentile for gestational age) Previous history of GDM
Exclusion criteria
Exclusion criteria: Diagnosis of overt DM by any value above the cutoff given by ADA i.e. FPG more than equalto 126 mg/dl; HbA1c more than equal to 6.5%; or 2 hour post 75 grams OGTT value more than equal to 200 mg/dl Patient having multi-fetal gestation Patients with Heart disease Chronic hypertension or preeclampsia Autoimmune disease Haematological disease Liver disease Chronic kidney disease Alcohol and/or drug addiction Immunosuppressive treatment Malignant diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Predictive value of serum Irisin levels during early pregnancy and development of GDM between 24th â?? 28th week of pregnancy.Timepoint: Before 12 week weeks-fasting plasma glucose, serum Irisin, 1 hour post OGTT and 2 hour post OGTT plasma glucose. Between 24-28 weeks-fasting plasma glucose, serum Irisin, 1 hour post OGTT and 2 hour post OGTT glucose. | — |
Secondary
| Measure | Time frame |
|---|---|
| Relationship of fasting plasma glucose (FPG) during early pregnancy and the development of GDM during 24th â?? 28th week of pregnancy Correlation between FPG and HbA1c during early pregnancy Relationship between HbA1c in early pregnancy and development of GDM during 24th â?? 28th week of pregnancyTimepoint: Before 12 week weeks-fasting plasma glucose,1 hour post OGTT ,2 hour post OGTT plasma glucose,HbA1c Between 24-28 weeks-fasting plasma glucose,1 hour post OGTT ,2 hour post OGTT glucose,HbA1c | — |
Countries
India
Contacts
Public ContactDr Devadarshini Sahoo
MKCG Medical College and Hospital
Outcome results
None listed