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Comparative evaluation of treatment of infrabony defects with PRF or combination with biphasic calcium phosphate bone graft

Comparative evaluation of treatment of infrabony defects with platelet richfibrin alone or in combination with biphasic calcium phosphate bone graft;A Randomised controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/09/021378
Enrollment
50
Registered
2019-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R69- Illness, unspecified

Interventions

Intervention1: PRF alone: To evaluate and compare the clinical and radiographic parameters before and after the use of PRF alone in the treatment of infrabony defect PRF Administered locally to the si

Sponsors

Sruthy Madhusudanan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: I. Patients without systemic diseases or conditions that could influence therapy outcome II. Patients who are not taking any medication that would affect periodontal healing III. High standards of oral hygiene (Oâ??Leary et al.: plaque control record [PCR] IV. compliance with the maintenance program V. presence of at least one infrabony defect with a PD >= 6 mm after reevaluation of the hygienic phase and an infrabony component of >=3 mm as detected on radiographs and exhibiting a 1- or 2-wall infrabony defect VI. presence of at least 2 mm of keratinized tissue on the buccal aspect of the selected tooth VII. Teeth have to be vital or properly treated endodontically

Exclusion criteria

Exclusion criteria: 1) Heavy smokers ( >10 cigarettes/day) 2) teeth with Class II or III furcation involvement(Glickman classification) 3) mobility >grade II(Glickman classification) 4) Strictly or predominantly 3-wall defects

Design outcomes

Primary

MeasureTime frame
1) To evaluate and compare the clinical and radiographic parameters before and after the use of PRF alone and PRF in combination with biphasic tricalcium phosphate bone graft in the treatment of infrabony defect 2) To compare the efficacy of PRF alone with PRF and biphasic tricalcium phosphate bone graft combination in treatment of infrabony defects using clinical and radiographic parametersTimepoint: 10mins

Secondary

MeasureTime frame
To evaluate and compare the alkaline phosphatase level in gingival crevicular fluid before and after the use of PRF alone and PRF and biphasic tricalcium phosphate bone graft combinationTimepoint: 15mins

Countries

India

Contacts

Public ContactSruthy Madhusudanan

PMS college of dental sciences affliated to KUHAS

ambiliranjith@yahoo.com9745422424

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026