FindTrial
Sign In

Effect of drug vitamin C and N Acetyl Cysteine given into vein for after surgery pain and opioid drug utilisation in gynaecologic cancer surgeries done laparoscopically

Effect of intravenous Vitamin C and N Acetyl Cysteine on postoperative pain and opioid consumption after laparoscopic Gynaec oncology surgery- A Comparative randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2019/09/021332
Enrollment
300
Registered
2019-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C55- Malignant neoplasm of uterus, partunspecified

Interventions

Intervention1: Intravenous Vitamin C: Intravenous Vitamin C at the dose of 3grams intraoperatively over the period of 30 minutes Control Intervention1: N Acetyl Cysteine intravenous: Intravenous N Ace

Sponsors

Rajiv Gandhi University Of Health Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with endometrial and cervix cancer posted for laparoscopic surgeries

Exclusion criteria

Exclusion criteria: Patients with history of coagulation abnormalities, liver failure, renal failure

Design outcomes

Primary

MeasureTime frame
Opioid consumption postoperatively and pain scoresTimepoint: Visual Analogue pain scale postoperatively for 24 hours—

Secondary

MeasureTime frame
1)To study the incidence of side effects associated with the drugs. 2) To study the pain scores between two groups 3) To study the time requirement for first dosing of rescue analgesics Timepoint: 24hrs post surgery—

Countries

India

Contacts

Public ContactRachana N D

Kidwai Cancer Institute

rachanakiran84@gmail.com9886110605

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026